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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
13.64
Human Site:
S629
Identified Species:
21.43
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
S629
K
D
E
E
R
R
E
S
R
I
Q
S
Y
S
P
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
S629
K
D
E
E
R
R
E
S
R
I
Q
S
Y
S
P
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
G381
A
L
A
L
G
G
A
G
A
Y
P
L
D
V
E
Dog
Lupus familis
XP_534537
1097
121903
E616
Y
A
F
K
F
F
M
E
Q
H
V
E
N
V
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
S628
K
D
E
E
R
R
E
S
R
I
Q
S
Y
S
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
R620
D
E
E
R
R
E
S
R
I
Q
S
Y
S
P
Q
Chicken
Gallus gallus
XP_419666
1136
127431
S635
K
D
E
E
R
R
E
S
R
I
Q
S
Y
S
P
Frog
Xenopus laevis
NP_001087838
1118
125984
A624
I
Q
S
Y
S
P
Q
A
F
K
F
F
M
E
Q
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
G615
M
Q
R
V
G
L
S
G
D
A
Q
E
Q
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
K618
A
S
S
S
T
S
C
K
K
I
K
H
A
S
P
Honey Bee
Apis mellifera
XP_395146
1137
124999
C665
K
E
E
E
R
R
D
C
K
V
R
N
Y
S
P
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
E48
N
R
L
K
K
L
E
E
D
I
S
A
R
G
L
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
P705
R
H
K
E
R
Y
E
P
R
V
K
T
Y
N
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
Q328
S
E
E
R
K
S
R
Q
L
S
S
L
G
K
K
Red Bread Mold
Neurospora crassa
P38679
598
67999
R170
R
A
R
E
R
N
Q
R
Q
S
E
M
E
Q
K
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
100
0
0
N.A.
100
N.A.
N.A.
13.3
100
0
6.6
N.A.
20
53.3
13.3
40
P-Site Similarity:
100
100
0
13.3
N.A.
100
N.A.
N.A.
20
100
13.3
6.6
N.A.
33.3
93.3
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
14
7
0
0
0
7
7
7
7
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% C
% Asp:
7
27
0
0
0
0
7
0
14
0
0
0
7
0
0
% D
% Glu:
0
20
47
47
0
7
40
14
0
0
7
14
7
7
7
% E
% Phe:
0
0
7
0
7
7
0
0
7
0
7
7
0
0
0
% F
% Gly:
0
0
0
0
14
7
0
14
0
0
0
0
7
7
0
% G
% His:
0
7
0
0
0
0
0
0
0
7
0
7
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
7
40
0
0
0
0
7
% I
% Lys:
34
0
7
14
14
0
0
7
14
7
14
0
0
7
14
% K
% Leu:
0
7
7
7
0
14
0
0
7
0
0
14
0
0
7
% L
% Met:
7
0
0
0
0
0
7
0
0
0
0
7
7
7
0
% M
% Asn:
7
0
0
0
0
7
0
0
0
0
0
7
7
7
0
% N
% Pro:
0
0
0
0
0
7
0
7
0
0
7
0
0
7
47
% P
% Gln:
0
14
0
0
0
0
14
7
14
7
34
0
7
7
14
% Q
% Arg:
14
7
14
14
54
34
7
14
34
0
7
0
7
0
7
% R
% Ser:
7
7
14
7
7
14
14
27
0
14
20
27
7
40
0
% S
% Thr:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% T
% Val:
0
0
0
7
0
0
0
0
0
14
7
0
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
7
0
0
0
7
0
7
40
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _